Pancreatitis is an inflammation of the pancreas caused by
leakage of the digestive enzymes and causing the pancreas to "digest
itself." Pancreatitis can be acute (sudden) or chronic (happening over a
course of time.) Both acute and chronic forms are serious and can be
life-threatening. Middle-aged dogs appear to be at increased risk of developing
pancreatitis. Certain breeds are more prone to the disease, particularly
Schnauzers and Yorkshire terriers.
Pancreatitis is more common in overweight dogs. When pancreatitis occurs in an
overweight dog it is more likely to cause serious illness.
Causes of Pancreatitis
Multiple factors can contribute to the development of
pancreatitis including:
Certain medications: The medications most suspected of
causing pancreatitis include azathioprine (Imuran Rx), potassium bromide (used
for seizure control), l-asparaginase (a chemotherapeutic agent) and zinc used
as a dietary supplement.
- Infections
- Metabolic
disorders: Including hyperlipidemia (high amounts of lipid in the blood)
and hypercalcemia (high amounts of calcium in the blood)
- Obesity
- Trauma
and shock
- Scorpion
stings
Nutrition also plays a major role. Dogs with high-fat diets,
dogs that have recently eaten the trash, are fed table scraps, or 'steal'
greasy people food have a higher incidence of the disease. In addition, dogs
that have previously had pancreatitis or abdominal surgery appear to be more at
risk.
Preventing Pancreatitis
Because fatty foods are a common cause of pancreatitis, it
is good to limit the amount of fat in your dog?s diet. Be especially careful
around the holidays as extra table scraps and fat trimmings in the garbage can
trigger pancreatitis.
Symptoms of Pancreatitis
The signs can vary from mild gastrointestinal upset to
collapse and death. However, most dogs have some signs of GI upset, such as:
- Vomiting
- Not
eating
- Painful
abdomen, hunched appearance
- Fever
or below-normal body temperature
- Diarrhea
- Depression
- Dehydration
which can be evaluated by noting sunken eyes, dry mouth, and increased
skin turgor (skin tents when pinched)
- Difficulty
in breathing
- Heart
arrhythmias
- Inflammation
of organs that surround the pancreas
- Infection
and hemorrhages throughout the body
All or some of the signs may be present with pancreatitis, but are not specific
for pancreatitis, and can be seen with many gastrointestinal diseases and
conditions.
Diagnosing Pancreatitis
Pancreatitis can be diagnosed by looking at blood
chemistries and biopsies. While biopsy is the gold standard, unless surgery is
called for, these are not generally performed because of their invasive nature.
Treating Pancreatitis
The goal of treatment is to rest the pancreas, provide
supportive care and control complications. If vomiting is severe, treatment
usually consists of withholding all food, water, and oral medications for 24
hours to stop the stimulation of the pancreas. Depending on the dog's response,
food can be reintroduced after a day. At that time, the dog should be fed
small, bland, easily digestible meals that are high-carbohydrate, low-fat. Over
a period of a week, meal size and quantity of food can be increased. The dog
may need to stay on a special diet for life, or it may be possible to gradually
reintroduce the former diet. High-fat diets or treats should be avoided. Since
dehydration and electrolyte imbalances are common in dogs with acute
pancreatitis and water intake is often restricted, fluid therapy is usually
needed. Fluids are either given subcutaneously or intravenously.
Dogs that experience severe pain can be treated with pain
relievers such as meperidine or butorphanol. Antibiotics are often administered
prophylactically to protect against infection. If the pancreatitis was caused
by a medication, the medication should be stopped. If it was caused by a toxin,
infection, or other condition, the appropriate therapy for the underlying
condition should be started. In rare instances where there are intestinal
complications or the development of a pancreatic abscess, surgery may be
necessary.
Caring for Dogs with Pancreatitis
Pancreatitis can be a very unpredictable disease. In most
cases, if the pancreatitis was mild and the pet only had one episode, chances
of recovery are good and avoiding high fat foods may be all that is necessary
to prevent recurrence or complications. In other cases, what appears to be a
mild case may progress, or may be treated successfully only to have recurrences,
sometimes severe. Dogs with severe pancreatitis can recover, but may also
develop fatal complications. The risk of developing fatal pancreatitis is
increased in dogs that are overweight, or have diabetes mellitus,
hyperadrenocorticism, hypothyroidism, gastrointestinal tract disease, and
epilepsy. Dogs that suffer repeated bouts of pancreatitis may need to be fed
low-fat diets to prevent recurrence.
Some dogs develop chronic pancreatitis, which can lead to
diabetes mellitus and/or pancreatic insufficiency, also called maldigestion
syndrome. In pancreatic insufficiency, the nutrients in food are passed out in
the feces undigested. Dogs with this disease often has a ravenous appetite,
diarrhea, and weight loss. Even though he is eating, he could literally starve
to death. Treatment for pancreatic insufficiency is lifelong and expensive, but
is possible. The dog?s digestive enzymes are replaced through a product
processed from pancreases of hogs and cattle which contain large quantities of
the digestive enzymes. A change in diet with added nutritional supplements may
also be necessary.
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